Wednesday, August 21, 2013

Chest Pain in a 61 year old male. Inferior STEMI without inferior ST elevation.

This 61 year old has a h/o CABG 20 years prior.  Onset of chest pain 1 hour prior to calling 911.  Here is the prehospital ECG:

Sinus rhythm.  There is an inverted T-wave in I and aVL, with very minimal ST depression, but no inferior ST elevation.  The T-wave in III does not have the normal amount of upward concavity.  There is a minmal right ventricular conduction delay (R' in V1). There is a biphasic T-wave in V2, and a quite large T-wave in V3 as well as inversion in V5
The only finding that is highly suspicious for ACS in this tracing is the ST segment and T-wave in aVL.  These two findings are early findings in inferior STEMI.

He arrived in the ED and had this ECG:

Now the findings in aVL are more pronounced, and the T-wave in lead III looks hyperacute, but still without ST elevation.  Also, there is ST elevation in V1, a common sign of right ventricular STEMI

A right sided ECG was obtained.  (V1-V6 are really V1R through V6R, on the right chest):

There is ST elevation throughout  the right sided leads (V2R-V6R).  There is still no ST elevation in inferior leads.  Only 0.5 mm is required for the diagnosis of RV MI, with reasonable sensitivity and specificity.  Here there is at least 1 mm in V2R through V4R)

The emergency physician activated the cath lab, and the interventionalist was not convinced but was persuaded to take the patient to the cath lab.

There was a 100% occluded proximal Right coronary artery.  It was opened and stented.

12 hour peak troponin I (for what that is worth) was 37 ng/ml.

Here is the post cath ECG:
Hyperacute T-waves have resolved.  Reciprocal ST depression is resolved.  There is still minimal ST elevation in V1, which may be the patient's baseline.  The T-waves in V2 and V3 have significantly changed.  I do not have enough details of the cath report and anatomy to explain these T-waves in V2 and V3; perhaps they are related to the right ventricular ischemia.


Lessons: 

In our study of inferior MI vs. other etiologies inferior STEMI, 28% had ST depression and T-wave inversion in lead aVL before they had 1 mm of ST elevation in any inferior lead.  This case is especially unusual in that no amount of inferior ST elevation was present; the diagnosis relied upon reciprocal findings and right ventricular findings.

I don't have the whole cath  report, nor an echo showing  inferior wall motion abnormality.  One might argue that this was an RV MI only, without inferior wall involvement (a non-dominant RCA that only supplies the RV).  However, there are clearly inferior hyperacute T-waves which resolve, so this is an inferior wall MI.

4 comments:

  1. There seem to be Wellen's waves in present in the lateral precordial leads. Is it possible that the pt has a lesion in his LAD that is the cause of the anterior injury pattern 2nd to a "reverese coronary steal" phenomenom? Caused by blood being shunted from the proximal/mid-LAD to the distal-LAD to make up for the deficit from an occluded RCA?

    B/c it looks like areas supplied by the proximal RCA are more ischemic(e.g. the STE in R sided leads + the 2nd degree type II SA block + PR seg elevation in aVR and V1 possibly indicating an atrial infarction) than areas that are supplied by the distal RCA.

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    1. Your thoughts are particulary plausible given that the patient has had a CABG. I don't know his anatomy, but it is conceivable that a graft could perfuse the distal RCA and not the proximal, and that there could be trouble with the graft to the LAD as well. I don't have the cath report.

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  2. Dr. Smith,
    In the post cath ECG, there is now a biphasic T wave in aVL, however it is "down-up", rather than "up-down".

    Is this reciprocal to the reperfusion T wave you'd see (up-down) in the inferior leads? Although not visible in the inferior leads (much like the ST elevation was), can the reciprocal of reperfusion T waves be visible in aVL?

    thanks,
    David

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    1. Dave,
      Great observation. There are two reasons for a down-up T-wave: 1) reciprocal to reperfusion T-wave 2) the "up" portion is really a U-wave, think hypoK. This one in aVL is reciprocal to reperfusion in III.
      Steve

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